Hoth Therapeutics, Inc. (Nasdaq: HOTH) shared promising news regarding HT-ALZ, their therapeutic under development for Alzheimer's disease. 

Positive preclinical results surpassed their previous study, with the higher dose showing the most beneficial effects in a spatial memory test conducted at Washington University in St. Louis. 

Alzheimer's, the leading cause of dementia, affects memory and cognitive abilities, significantly impacting daily life. 

Following this announcement, $HOTH closed at $3.35, reflecting a significant increase of $1.47 (+78.19%).

Advanced Micro Devices, Inc. (Nasdaq: AMD), a prominent semiconductor company known for its innovative products, had its price target raised from $110 to $150 by Piper Sandler.

With $AMD closing at $124.23 on Tuesday, this adjusted price target suggests a potential upside of $25.77 (20.74%) based on Piper Sandler's view.

Agenus Inc. (Nasdaq: AGEN), a biotechnology company dedicated to developing breakthrough immunotherapies, was initiated with an Outperform rating by Robert W. Baird, along with a price target of $8. 

Despite $AGEN closing at $1.85 on Tuesday, Robert W. Baird's positive outlook implies a potential upside of $6.15 (332.43%).

Vale S.A. (NYSE: VALE), one of the world's largest mining companies, experienced an upgrade from Sector Perform to Outperform by RBC Capital Markets, accompanied by a price target increase from $13 to $15. 

Given $VALE closing price of $13.73 on Tuesday, this adjustment suggests a potential upside of $1.27 (9.25%), according to RBC Capital Markets' view.

Airbnb, Inc. (Nasdaq: ABNB), a leading online vacation rental marketplace, was initiated with a Neutral rating by Wedbush, with a price target set at $130. 

Despite $ABNB closing at $117.30 on Tuesday, this price target implies a potential upside of $12.70 (10.82%) based on Wedbush's analysis

Stem, Inc. (NYSE: STEM), an innovative energy storage solutions provider, caught the attention of Janney, who initiated coverage with a Buy rating and set a price target of $12. 

Although $STEM closed at $5.80 on Tuesday, Janney's positive outlook indicates a potential upside of $6.20 (106.90%).

These potential upsides are based on the assessments and views of the respective brokerage firms, investment firms, or analysts, highlighting the market's expectations and sentiment towards each company's future performance.

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