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Horizon Therapeutics' Daxdilimab Trial Falls Short on Primary Endpoint

  • July 23rd, 2023
  • 205 views

Horizon Therapeutics plc (Nasdaq: HZNP) reported disappointing results from its Phase 2 clinical trial for daxdilimab in the treatment of systemic lupus erythematosus (SLE), the most common type of lupus. The trial did not show a statistically significant separation between daxdilimab and placebo on the primary endpoint, which measured low SLE disease activity.

However, the company reported numerical differences in other endpoints and stated that there were no safety concerns. Horizon Therapeutics remains committed to assessing the full dataset. The company's daxdilimab trials in alopecia areata, discoid lupus erythematosus, and lupus nephritis are still ongoing.

Following the announcement, $HZNP declined by $1.18 (-1.17%) to $100.00 in after-hours trading on Friday.

 

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