Momentum Shift: Biomea Unveils Promising Type 2 Diabetes Study Data for BMF-219
- June 24th, 2023
- 337 views
Biomea Fusion, Inc. (Nasdaq: BMEA) shared new clinical data from its ongoing Phase II study (COVALENT-111) evaluating BMF-219, an oral covalent menin inhibitor, in patients with type 2 diabetes (T2D).
T2D is a chronic metabolic disorder characterized by high blood sugar levels due to insulin resistance and inadequate insulin production. The data demonstrated positive results in glycemic control even after therapy cessation, indicating the potential disease-modifying effects of BMF-219.
The drug targets beta cell loss, a crucial factor in the development of both type 2 and type 1 diabetes. BMF-219 exhibited three modes of action in pre-clinical studies: beta cell regeneration, reactivation, and preservation.
The observed increase in C-peptide levels post-treatment cessation marks a significant milestone in diabetes treatment. Biomea Fusion plans to further explore the drug's impact by evaluating additional dose levels and durations in a larger patient population.
On Friday, $BMEA closed at $30.67, experiencing a decrease of $1.92 (-5.89%).
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